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Follow your instincts. Do the kind of writing you love to do and do best. 'Stiff' was an oddball book - I mean, a funny book about cadavers? - and I worried that it would be too unconventional. In the end, that's what has made it a success, I think.
And I think that being able to make people laugh and write a book that's funny makes the information go down a lot easier and it makes it a lot more fun to read easier to understand and often stronger. So there's all kinds of advantages to it.
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