This business is ephemeral, and you have to maintain a healthy cynicism about it. There's a 'flavour of the month' aspect to it, so you have to keep moving on and mutating.

An Internet meme is a hijacking of the original idea. Instead of mutating by random change and spreading by a form of Darwinian selection, Internet memes are altered deliberately by human creativity. There is no attempt at accuracy of copying, as with genes - and as with memes in their original version.