"We each have within ourselves the ability to shape our own destinies. That much we understand. But, more important, each of us has an equal ability to shape the destiny of the universe. Ah, that you find more difficult to believe. But I tell you it is so. You do not have to be the leader of the Council. You do not have to be king or monarch or the head of a clan to have a significant impact on the world around you.

If we wish to draw philosophical conclusions about our own existence, our significance, and the significance of the universe itself, our conclusions should be based on empirical knowledge. A truly open mind means forcing our imaginations to conform to the evidence of reality, and not vice versa, whether or not we like the implications.

What really frightens and dismays us is not external events themselves, but the way in which we think about them. It is not things that disturb us, but our interpretation of their significance.

"Sometimes the most remarkable things seem commonplace. I mean when you think about it jet travel is pretty freaking remarkable. You get in a plane it defies the gravity of a entire planet by exploiting a loophole with air pressure and it flies across distances that would take months or years to cross by any means of travel that has been significant for more than a century or three. You hurtle above the earth at enough speed to kill you instantly should you bump into something and you can only breathe because someone built you a really good tin can that seems tight enough to hold in a decent amount of air. Hundreds of millions of man-hours of work and struggle and research blood sweat tears and lives have gone into the history of air travel and it has totally revolutionized the face of our planet and societies.

I've always thought people would find a lot more pleasure in their routines if they burst into song at significant moments.

Every man is more than just himself; he also represents the unique, the very special and always significant and remarkable point at which the world's phenomena intersect, only once in this way, and never again. That is why every man's story is important, eternal, sacred; that is why every man, as long as he lives and fulfills the will of nature, is wondrous, and worthy of consideration. In each individual the spirit has become flesh, in each man the creation suffers, within each one a redeemer is nailed to the cross.

The span of three or four minutes is pretty insignificant in the scheme of things. People lose hundreds of minutes everyday, squandering them on trivial things. But sometimes in those fragments of time, something can happen you'll remember the rest of your life.

Without God, life has no purpose, and without purpose, life has no meaning. Without meaning, life has no significance or hope.

No matter what happened yesterday it is insignificant when compared to what lies within the core of your being today.

The life of every individual, viewed as a whole and in general, and when only its most significant features are emphasized, is really a tragedy; but gone through in detail it has the character of a comedy.

Our most significant opportunities will be found in times of greatest difficulty.

There is something incredibly nostalgic and significant about the annual cascade of autumn leaves.

We all have such fateful objects - it may be a recurrent landscape in one case, a number in another - carefully chosen by the Gods to attract events of specific significance for us: here shall John always stumble; there shall Jane's heart always break.

All that happens means something; nothing you do is ever insignificant.

You learn something valuable from all of the significant events and people, but you never touch your true potential until you challenge yourself to go beyond imposed limitations.

Our lives are not as limited as we think they are; the world is a wonderfully weird place; consensual reality is significantly flawed; no institution can be trusted, but love does work; all things are possible; and we all could be happy and fulfilled if we only had the guts to be truly free and the wisdom to shrink our egos and quit taking ourselves so damn seriously.

Learn to light a candle in the darkest moments of someone's life. Be the light that helps others see; it is what gives life its deepest significance.

To love. To be loved. To never forget your own insignificance. To never get used to the unspeakable violence and the vulgar disparity of life around you. To seek joy in the saddest places. To pursue beauty to its lair. To never simplify what is complicated or complicate what is simple. To respect strength, never power. Above all, to watch. To try and understand. To never look away. And never, never to forget.

Romance is thinking about your significant other, when you are supposed to be thinking about something else.

Only once in your life, I truly believe, you find someone who can completely turn your world around. You tell them things that you've never shared with another soul and they absorb everything you say and actually want to hear more. You share hopes for the future, dreams that will never come true, goals that were never achieved and the many disappointments life has thrown at you. When something wonderful happens, you can't wait to tell them about it, knowing they will share in your excitement. They are not embarrassed to cry with you when you are hurting or laugh with you when you make a fool of yourself. Never do they hurt your feelings or make you feel like you are not good enough, but rather they build you up and show you the things about yourself that make you special and even beautiful. There is never any pressure, jealousy or competition but only a quiet calmness when they are around. You can be yourself and not worry about what they will think of you because they love you for who you are. The things that seem insignificant to most people such as a note, song or walk become invaluable treasures kept safe in your heart to cherish forever. Memories of your childhood come back and are so clear and vivid it's like being young again. Colours seem brighter and more brilliant. Laughter seems part of daily life where before it was infrequent or didn't exist at all. A phone call or two during the day helps to get you through a long day's work and always brings a smile to your face. In their presence, there's no need for continuous conversation, but you find you're quite content in just having them nearby. Things that never interested you before become fascinating because you know they are important to this person who is so special to you. You think of this person on every occasion and in everything you do. Simple things bring them to mind like a pale blue sky, gentle wind or even a storm cloud on the horizon. You open your heart knowing that there's a chance it may be broken one day and in opening your heart, you experience a love and joy that you never dreamed possible. You find that being vulnerable is the only way to allow your heart to feel true pleasure that's so real it scares you. You find strength in knowing you have a true friend and possibly a soul mate who will remain loyal to the end. Life seems completely different, exciting and worthwhile. Your only hope and security is in knowing that they are a part of your life.

Clinton is a big personality who has led a big life and for some of the media conventional wisdom to boil it down to a view that 'all people are really interested in' are a few moments of madness in the Oval Office gets him the importance of the presidency and the significance of his life all wrong.

As the President has indicated my life has been a life of travel - for 60 years constantly moving over the wide world on journeys which first and last have taken me to 83 countries and what is more significant to most of them again and again.

Life is a series of steps. Things are done gradually. Once in a while there is a giant step but most of the time we are taking small seemingly insignificant steps on the stairway of life.

Drink and be thankful to the host! What seems insignificant when you have it is important when you need it.