When trying to remember my share in the glow of the eternal present, in the smile of God, I return to my childhood, too, for that is where the most significant discoveries turn up.

The scientific content of Genesis 1-11 holds special significance for me because it revolutionized my thinking and, thus, changed my life's direction. Until I reached my late teens, my singular passion was science, astronomy in particular. My life's purpose was to learn more about the universe; nothing beyond that really interested me.

For me, science is already fantastical enough. Unlocking the secrets of nature with fundamental physics or cosmology or astrobiology leads you into a wonderland compared with which beliefs in things like alien abductions pale into insignificance.

Saturdays and Sundays, America in the year 2009 does not in some ways differ significantly from the country that existed almost 50 years ago. This is truly sad.

Digital intimacy ruins the appetite for the real thing. So, when kids are gaming or even when spouses are gaming, they lose their appetite for genuine intimacy. Kids lose their appetite for getting their intimacy needs, their hunger for significance and attachment, with the family, and it erodes the relationship between them and their parents.

I think one of the most important things in a relationship is caring for your significant other through good times and bad.

Killing animals and eating meat have been significant components of human evolution that had a synergistic relationship with other key attributes that have made us human, with larger brains, smaller guts, bipedalism, and language.

Every man who knows how to read has it in his power to magnify himself, to multiply the ways in which he exists, to make his life full, significant and interesting.

There is an urgent need to stop subsidizing the fossil fuel industry, dramatically reduce wasted energy, and significantly shift our power supplies from oil, coal, and natural gas to wind, solar, geothermal, and other renewable energy sources.

In my opinion, the most significant works of the twentieth century are those that rise beyond the conceptual tyranny of genre; they are, at the same time, poetry, criticism, narrative, drama, etc.

I guess the two Manifesto, Communicating Vessels, Mad Love, and some of his poetry made a significant mark on me but as far as bringing a literary element into the music I see it as a much broader assimilation.

Nothing is too small. Nothing is too, quote-unquote, ordinary or insignificant. Those are the things that make up the measure of our days, and they're the things that sustain us. And they're the things that certainly can become worthy of poetry.

Definitely, when I have a place and I'm going to be there for any significant amount of time, I want to have dogs. I like a pet you can have some fun with and who does everything you do.

Terrorism is a significant threat to peace and security, prosperity and people.

I am very hopeful that my personal success in Qatar will ignite others, especially those in the so-called non-traditional sports, to try even harder because now they can see for themselves that significant achievements can be attained. But let me stress that it takes a lot of work - in fact, very hard work - mixed with very heavy doses of patience.

Human bodies are designed for regular physical activity. The sedentary nature of much of modern life probably plays a significant role in the epidemic incidence of depression today. Many studies show that depressed patients who stick to a regimen of aerobic exercise improve as much as those treated with medication.

Every significant event that takes place in our lives is set to some kind of music.

To grasp the full significance of life is the actor's duty; to interpret it his problem; and to express it his dedication.

What I had said in the morning was that this is what we know has happened, but there has been no significant off-site release. Only to find out moments later that, in fact, there had been an off-site release. I still haven't gotten over that.

A human being would certainly not grow to be seventy or eighty years old if this longevity had no meaning for the species. The afternoon of human life must also have a significance of its own and cannot be merely a pitiful appendage to life's morning.

I have profoundly mixed feelings about the Affordable Care Act. What I love about it is its impulse. It attempts to deal with this intractable problem in American health care life, which is that a significant portion of the population does not have access to quality medical care.

For me, the ability to use semiconductor sequencing to provide a medical diagnosis in just a few hours that once took days is a crucial step in saving the lives of patients. This is particularly significant for the treatment of sepsis, where every minute matters.

It's very different than it use to be. I think everybody has a lot more experience in how to be in a relationship - whether it's a marriage or a significant other or a business or a friend.

Unfenced by law, the unmarried lover can quit a bad relationship at any time. But you - the legally married person who wants to escape doomed love - may soon discover that a significant portion of your marriage contract belongs to the State, and that it sometimes takes a very long while for the State to grant you your leave.