Every man who knows how to read has it in his power to magnify himself, to multiply the ways in which he exists, to make his life full, significant and interesting.

There is an urgent need to stop subsidizing the fossil fuel industry, dramatically reduce wasted energy, and significantly shift our power supplies from oil, coal, and natural gas to wind, solar, geothermal, and other renewable energy sources.

In my opinion, the most significant works of the twentieth century are those that rise beyond the conceptual tyranny of genre; they are, at the same time, poetry, criticism, narrative, drama, etc.

I guess the two Manifesto, Communicating Vessels, Mad Love, and some of his poetry made a significant mark on me but as far as bringing a literary element into the music I see it as a much broader assimilation.

Nothing is too small. Nothing is too, quote-unquote, ordinary or insignificant. Those are the things that make up the measure of our days, and they're the things that sustain us. And they're the things that certainly can become worthy of poetry.

Definitely, when I have a place and I'm going to be there for any significant amount of time, I want to have dogs. I like a pet you can have some fun with and who does everything you do.

Terrorism is a significant threat to peace and security, prosperity and people.

I am very hopeful that my personal success in Qatar will ignite others, especially those in the so-called non-traditional sports, to try even harder because now they can see for themselves that significant achievements can be attained. But let me stress that it takes a lot of work - in fact, very hard work - mixed with very heavy doses of patience.

Human bodies are designed for regular physical activity. The sedentary nature of much of modern life probably plays a significant role in the epidemic incidence of depression today. Many studies show that depressed patients who stick to a regimen of aerobic exercise improve as much as those treated with medication.

Every significant event that takes place in our lives is set to some kind of music.

What I had said in the morning was that this is what we know has happened, but there has been no significant off-site release. Only to find out moments later that, in fact, there had been an off-site release. I still haven't gotten over that.

I have profoundly mixed feelings about the Affordable Care Act. What I love about it is its impulse. It attempts to deal with this intractable problem in American health care life, which is that a significant portion of the population does not have access to quality medical care.

For me, the ability to use semiconductor sequencing to provide a medical diagnosis in just a few hours that once took days is a crucial step in saving the lives of patients. This is particularly significant for the treatment of sepsis, where every minute matters.

It's very different than it use to be. I think everybody has a lot more experience in how to be in a relationship - whether it's a marriage or a significant other or a business or a friend.

Unfenced by law, the unmarried lover can quit a bad relationship at any time. But you - the legally married person who wants to escape doomed love - may soon discover that a significant portion of your marriage contract belongs to the State, and that it sometimes takes a very long while for the State to grant you your leave.

A significant fraction of evangelical voters appear more likely to ignore the candidates' specific economic and foreign policy platforms in favor of concerns about gay marriage or abortion.

The legal difference between the sit-ins and the Freedom Riders was significant.

We're involved right now in some very significant legal battles and it would be the wrong thing for me to do to step out in the middle of those battles.

In legal language, a covenant generally denotes an agreement between two or more parties. But in a religious context, a covenant is much more significant. It is a sacred promise with God. He fixes the terms.

Painful as it may be, a significant emotional event can be the catalyst for choosing a direction that serves us - and those around us - more effectively. Look for the learning.

I became obsessed with making more and more tiny things. I think I was trying to find a way of compensating for my embarrassment at having learning difficulties: people had made me feel small so I wanted to show them how significant 'small' could be.

I believe that the testing of the student's achievements in order to see if he meets some criterion held by the teacher, is directly contrary to the implications of therapy for significant learning.

The longer we go without strong leadership from the Administration and until we see significant progress in the day-to-day lives of the Iraqi people, the more difficult it will become to sustain the support of the American people and Congress for the current course.

A significant number of pages and sentences that the administration wants to keep in a classified status have already been released publicly, some of it by public statements of the leadership of the CIA and the FBI.