There was a point in the late '90s where all the graduating M.B.A.'s wanted to start companies in Silicon Valley, and for the most part they were not actually qualified to do it.

Carbon nanotubes are amazing because they're really good electrical conductors, yet they are only a few atoms in diameter. You can make transistors out of them in the same way you can with silicon. At Berkeley, we made the narrowest device anybody had ever made. It was basically a single molecule.

At times it's as if the Silicon Valley inmates are running the VC asylum. But what might seem like unicorn-crazed chaos from the outside looking in is actually carefully structured.

In fact we put so many things in our mouths we constantly have to be reminded what not to eat. Look at that little package of silicon gel that's inside your sneakers. It says DO NOT EAT for a reason. Somewhere sometime some genius bought a pair of sneakers and said Ooooh look. They give you free mints with the shoes

Silicon Valley has some of the smartest engineers and technology business people in the world.

And I thought I would just share with you what science says today about silicone breast implants. If you have them you're healthier than if you don't. In fact there's no science that shows that silicone breast implants are detrimental and in fact they make you healthier.

Here in Silicon Valley I have taken part in hundreds of conversations trying to convince people to dive in and become entrepreneurs. All too often innovators with good safe jobs are unwilling to put their family's access to health care at risk by walking away from company-backed medical insurance.

I think there are four or five interesting pockets where a lot of cool technology companies are getting started. Chicago is one of them. New York is certainly another. Silicon Valley really dominates. And you're seeing some stuff out of Boston and Seattle and down South.

My friends are people who like building cool stuff. We always have this joke about people who want to just start companies without making something valuable. There's a lot of that in Silicon Valley.

So a more sensible thing it seemed to me was to go to Silicon Valley and be pushing on the technology companies to accelerate the use of audio and music in computers.

People always fear change. People feared electricity when it was invented didn't they? People feared coal they feared gas-powered engines... There will always be ignorance and ignorance leads to fear. But with time people will come to accept their silicon masters.

The way life manages information involves a logical structure that differs fundamentally from mere complex chemistry. Therefore chemistry alone will not explain life's origin any more than a study of silicon copper and plastic will explain how a computer can execute a program.