There can be no argument about the Lone Star State's significant contributions to American history, and we must remember the actions and the sacrifices of those who made Texas independence a reality.

As we explore ways to bring price relief and bolster our country's energy independence, one significant energy source has emerged as a potential solution, hydrogen fuel cells.

My country has contrived for me the most insignificant office that ever the invention of man contrived or his imagination conceived.

I don't have hard numbers about this, but the impression I get is that the amount of eyeballs you get from being on the humor shelf at Barnes & Noble - it is almost insignificant.

Humor is probably the most significant characteristics of the human mind. Far more significant than reason. In fact, reason is actually a very cheap commodity.

It has always surprised me how little attention philosophers have paid to humor, since it is a more significant process of mind than reason. Reason can only sort out perceptions, but the humor process is involved in changing them.

Humor is by far the most significant activity of the human brain.

I used to hear on the radio people like Jack Benny or Bob Hope, but I never had any interest in their type of humor. I thought that I could do something more substantially meaningful with significant, thoughtful, analytical reflections on real life situations.

Even a purely moral act that has no hope of any immediate and visible political effect can gradually and indirectly, over time, gain in political significance.

The capacity for hope is the most significant fact of life. It provides human beings with a sense of destination and the energy to get started.

While security of national leadership is of paramount significance, expenditure on permanent civil structures at the family home of the prime minister and chief minister from public exchequer will be a burden on their conscience.

Fellow citizens, we cannot escape history. We, of this Congress and this administration, will be remembered in spite of ourselves. No personal significance, or insignificance, can spare one or another of us. The fiery trial through which we pass will light us down in honor or dishonor, to the latest generation.

Nothing is insignificant in the history of a young community, and - above all - nothing seems impossible.

History is the interpretation of the significance that the past has for us.

Every time I attend an FBI graduation for new agents or new analysts at Quantico, a significant number of those graduates are former state and local officers, and I have the privilege of shaking their hands, presenting them with their credentials, and welcoming them to the FBI family.

Graduation is an important day. It is a significant achievement.

Twelve significant photographs in any one year is a good crop.

The person you consider ignorant and insignificant is the one who came from God, that he might learn bliss from grief and knowledge from gloom.

I think the iPhone was as significant an invention as the Gutenburg press, in terms of the future of humanity.

I hear you younger people saying how many friends they have on the Internet. That's nonsense. That's not friends, that's acquaintances. The word 'friendship' has lost its significance.

Nothing changes the gender equation more significantly than women's economic freedom.

Food and energy account for a significant portion of household budgets, so the Federal Reserve's inflation objective is defined in terms of the overall change in consumer prices.

Open your refrigerator, your freezer, your kitchen cupboards, and look at the labels on your food. You'll find 'natural flavor' or 'artificial flavor' in just about every list of ingredients. The similarities between these two broad categories are far more significant than the differences.

For working mothers, creating a work-life balance is critical, as we must ensure we do not neglect any significant part of our lives - our children, our family's health, our own health and fitness, our marriage, and, of course, our careers.