This Nation has realized significant environmental improvements over the last three decades.

Studies have shown that inmate participation in education, vocational and job training, prison work skills development, drug abuse, mental health and other treatment programs, all reduce recidivism, significantly.

My life has been a continuous fulfillment of dreams. It appears that everything I saw and did has a new, and perhaps, more significant meaning, every time I see it. The earth is good. It is a privilege to live thereon.

We need affordable space travel to inspire our youth, to let them know that they can experience their dreams, can set significant goals and be in a position to lead all of us to future progress in exploration, discovery and fun. Thanks to the X Prize for the inspiration.

A significant number of research studies have documented that heart disease is easily and almost completely preventable through a diet rich in plant produce and lower in processed foods and animal products.

Making changes in the fast food that makes up such a significant part of the American diet, even if the numbers aren't impressive, will have important health up sides.

While pimples are not as simple as too much milk or sugar in your diet, both have a significant impact. Nutritional deficiencies as well as excesses can worsen acne.

We believe that such a significant increase in longevity is due to the protective effect against cancer produced by caloric restriction - incidences fall by 40 percent if we compare them with the mice that produce more telomerase and have a normal diet - and, added to the presence of longer telomeres, this makes the mice live longer and better.

The new Zune may not be an iPod killer, but it does offer a clean interface, great industrial design, HD radio, and a subscription model for music, making it significantly less expensive for big users.

In any case, his judgment and set of values, acting alone or through his assistants, determine not only what is gold and what is dross but the design of the history which he creates out of the metal. The historian decides what is significant, and what is not.

Let it be your constant method to look into the design of people's actions, and see what they would be at, as often as it is practicable; and to make this custom the more significant, practice it first upon yourself.

I'm much more interested in what an actor has to say about something substantial and important than who they're dating or what clothes they're wearing or some other asinine, insignificant aspect of their life.

The Google algorithm was a significant development. I've had thank-you emails from people whose lives have been saved by information on a medical website or who have found the love of their life on a dating website.

It seems essential, in relationships and all tasks, that we concentrate only on what is most significant and important.

Without white South Africa realizing what it had done - and on the basis of that realization having the courage to ask for forgiveness - there can really be no significant movement.

What's happened with society is that we have created these devices, computers, which already can register and process huge amounts of information, which is a significant fraction of the amount of information that human beings themselves, as a species, can process.

The digital revolution is far more significant than the invention of writing or even of printing.

Every major communication tool on the Internet has spam and abuse problems. All email services, blogging services and social networks have to dedicate a significant amount of resources and time to fighting abuse and protecting their users.

Significant officials at publicly traded companies are casually and cavalierly engaged in insider trading. Because insider trading has as one of its elements communication, it doesn't take rocket science to realize it's nice to have the communication on tape.

Creating an overall healthy lifestyle for yourself doesn't require a radical diet or significant life change. In fact, it can be attained through common sense decisions about the way we eat, move, and live.

Being ready isn't enough; you have to be prepared for a promotion or any other significant change.

We must remember that one determined person can make a significant difference, and that a small group of determined people can change the course of history.

The specter of climate change threatens worsening natural disasters, rapid urbanization, forced migration, and economic hardship for the most vulnerable. Despite significant global advances, inability to effectively address epidemics and health emergencies still prevail and continuously threaten global health security and economic development.

Chance is hugely significant in biology. In fact, the presence of apparent randomness in so many aspects of biology - from mutations in DNA to the chance involved in that one sperm reaching that one egg that became you - suggests that randomness is useful, even necessary, in very many cases.